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99% of medications are still 100% potent and useful well beyond their expiration date, including epi pens. The only caveats are tetracycline antibiotics can potentially become toxic after their expiration, although no recent cases can be found to confirm this is still a issue nor deny it, liquids like penicillin oral solution may mold, and separate, and fluids like epipen can be come clouded, at which point it shouldn’t be used.
 

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Antibiotics, cancer meds, liquid pills are but a few of the meds that are actually harmful if used when expired, but other medications like pain killers for example could still be used from what I have read (& tried) but with reduced effectiveness. This does not mean one should take a higher dosage either to reach that same level of effectiveness fyi.
The only antibiotis that becomes harmful are tetracycline ones, outside of those the rest are decent.
 
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